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Down-Regulation of HLA Class I Antigen-Processing Molecules in Malignant Melanoma : Association with Disease Progression

Expression of the proteasome subunits LMP2 and LMP7, the MHC-encoded transporter subunits TAP1 and TAP2, and HLA Class I antigens was examined by immunoperoxidase staining in 10 nevi and 98 melanoma lesions (60 primary and 38 metastatic), because these molecules play an important role in the present...

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Detalhes bibliográficos
Main Authors: Kageshita, Toshiro, Hirai, Shunji, Ono, Tomomichi, Hicklin, Daniel J., Ferrone, Soldano
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866429/
https://ncbi.nlm.nih.gov/pubmed/10079252
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