Down-Regulation of HLA Class I Antigen-Processing Molecules in Malignant Melanoma : Association with Disease Progression

Expression of the proteasome subunits LMP2 and LMP7, the MHC-encoded transporter subunits TAP1 and TAP2, and HLA Class I antigens was examined by immunoperoxidase staining in 10 nevi and 98 melanoma lesions (60 primary and 38 metastatic), because these molecules play an important role in the present...

Full description

Saved in:
Bibliographic Details
Main Authors: Kageshita, Toshiro, Hirai, Shunji, Ono, Tomomichi, Hicklin, Daniel J., Ferrone, Soldano
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 1999
Subjects:
Regular Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866429/
https://ncbi.nlm.nih.gov/pubmed/10079252
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items