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TNF-α Receptor Knockout Mice Are Protected from the Fibroproliferative Effects of Inhaled Asbestos Fibers
We have demonstrated that C57BL/6–129 hybrid mice with genes for both the 55kd and 75kd receptors for TNF-α knocked out (TNF-αRKO) fail to develop fibroproliferative lesions after asbestos exposure. There is good evidence that TNF-α plays a major role in mediating interstitial pulmonary fibrosis. Ou...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Investigative Pathology
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1866331/ https://ncbi.nlm.nih.gov/pubmed/9846974 |
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