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TNF-α Receptor Knockout Mice Are Protected from the Fibroproliferative Effects of Inhaled Asbestos Fibers

We have demonstrated that C57BL/6–129 hybrid mice with genes for both the 55kd and 75kd receptors for TNF-α knocked out (TNF-αRKO) fail to develop fibroproliferative lesions after asbestos exposure. There is good evidence that TNF-α plays a major role in mediating interstitial pulmonary fibrosis. Ou...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Liu, Jing-Yao, Brass, David M., Hoyle, Gary W., Brody, Arnold R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Investigative Pathology 1998
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866331/
https://ncbi.nlm.nih.gov/pubmed/9846974
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