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Cyclic AMP signalling in Dictyostelium: G-proteins activate separate Ras pathways using specific RasGEFs
In general, mammalian Ras guanine nucleotide exchange factors (RasGEFs) show little substrate specificity, although they are often thought to regulate specific pathways. Here, we provide in vitro and in vivo evidence that two RasGEFs can each act on specific Ras proteins. During Dictyostelium develo...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1866193/ https://ncbi.nlm.nih.gov/pubmed/17380187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400936 |
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