Cyclic AMP signalling in Dictyostelium: G-proteins activate separate Ras pathways using specific RasGEFs

In general, mammalian Ras guanine nucleotide exchange factors (RasGEFs) show little substrate specificity, although they are often thought to regulate specific pathways. Here, we provide in vitro and in vivo evidence that two RasGEFs can each act on specific Ras proteins. During Dictyostelium develo...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Kae, Helmut, Kortholt, Arjan, Rehmann, Holger, Insall, Robert H, Van Haastert, Peter J M, Spiegelman, George B, Weeks, Gerald
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Scientific Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866193/
https://ncbi.nlm.nih.gov/pubmed/17380187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400936
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados