Determination of Kaposi's Sarcoma-Associated Herpesvirus C-Terminal Latency-Associated Nuclear Antigen Residues Mediating Chromosome Association and DNA Binding

Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen (LANA) tethers viral terminal repeat (TR) DNA to mitotic chromosomes to mediate episome persistence. The 1,162-amino-acid LANA protein contains both N- and C-terminal chromosome attachment regions. The LANA C-terminal do...

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Main Authors: Kelley-Clarke, Brenna, Ballestas, Mary E., Srinivasan, Viswanathan, Barbera, Andrew J., Komatsu, Takashi, Harris, Te-Ana, Kazanjian, Mia, Kaye, Kenneth M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866165/
https://ncbi.nlm.nih.gov/pubmed/17287261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01289-06
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