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The Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen 1 N Terminus Is Essential for Chromosome Association, DNA Replication, and Episome Persistence

To persist in latently infected, proliferating cells, Kaposi's sarcoma-associated herpesvirus (KSHV) episomes must replicate and efficiently segregate to progeny nuclei. Episome persistence in uninfected cells requires latency-associated nuclear antigen 1 (LANA1) in trans and cis-acting KSHV te...

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Detalhes bibliográficos
Main Authors: Barbera, Andrew J., Ballestas, Mary E., Kaye, Kenneth M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC303411/
https://ncbi.nlm.nih.gov/pubmed/14671111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.1.294-301.2004
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