Duplicated Sequence Motif in the Long Terminal Repeat of Maedi-Visna Virus Extends Cell Tropism and Is Associated with Neurovirulence

Maedi-visna virus (MVV) is a lentivirus of sheep causing chronic inflammatory disease of the lungs (maedi) and the nervous system (visna). We have previously shown that a duplicated sequence in the long terminal repeat (LTR) of MVV is a determinant of cell tropism. Here, we demonstrate that deletion...

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Detalhes bibliográficos
Main Authors: Óskarsson, Thórdur, Hreggvidsdóttir, Hulda S., Agnarsdóttir, Gudrún, Matthíasdóttir, Sigrídur, Ogmundsdóttir, Margrét H., Jónsson, Stefán R., Georgsson, Gudmundur, Ingvarsson, Sigurdur, Andrésson, Ólafur S., Andrésdóttir, Valgerdur
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866131/
https://ncbi.nlm.nih.gov/pubmed/17287273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02319-06
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