Simultaneous Mutations in CA and Vif of Maedi-Visna Virus Cause Attenuated Replication in Macrophages and Reduced Infectivity In Vivo

Maedi-visna virus (MVV) is a lentivirus of sheep sharing several key features with the primate lentiviruses. The virus causes slowly progressive diseases, mainly in the lungs and the central nervous system of sheep. Here, we investigate the molecular basis for the differential growth phenotypes of t...

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Detalhes bibliográficos
Main Authors: Gudmundsson, Bjarki, Jónsson, Stefán Ragnar, Ólafsson, Oddur, Agnarsdóttir, Gudrún, Matthíasdóttir, Sigrídur, Georgsson, Gudmundur, Torsteinsdóttir, Sigurbjorg, Svansson, Vilhjálmur, Kristbjornsdóttir, Helga Bryndís, Franzdóttir, Sigrídur Rut, Andrésson, Ólafur S., Andrésdóttir, Valgerdur
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1316017/
https://ncbi.nlm.nih.gov/pubmed/16306574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.24.15038-15042.2005
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