Simultaneous Mutations in CA and Vif of Maedi-Visna Virus Cause Attenuated Replication in Macrophages and Reduced Infectivity In Vivo

Maedi-visna virus (MVV) is a lentivirus of sheep sharing several key features with the primate lentiviruses. The virus causes slowly progressive diseases, mainly in the lungs and the central nervous system of sheep. Here, we investigate the molecular basis for the differential growth phenotypes of t...

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Bibliografske podrobnosti
Main Authors: Gudmundsson, Bjarki, Jónsson, Stefán Ragnar, Ólafsson, Oddur, Agnarsdóttir, Gudrún, Matthíasdóttir, Sigrídur, Georgsson, Gudmundur, Torsteinsdóttir, Sigurbjorg, Svansson, Vilhjálmur, Kristbjornsdóttir, Helga Bryndís, Franzdóttir, Sigrídur Rut, Andrésson, Ólafur S., Andrésdóttir, Valgerdur
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2005
Teme:
Genome Replication and Regulation of Viral Gene Expression
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1316017/
https://ncbi.nlm.nih.gov/pubmed/16306574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.24.15038-15042.2005
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