Visna Virus dUTPase Is Dispensable for Neuropathogenicity

The major part of the dUTPase-encoding region of the visna virus genome was deleted. Intracerebral injection of the mutant virus resulted in a somewhat reduced viral load compared to that resulting from injection of the wild type, especially in the lungs, but the neuropathogenic effects were compara...

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Detalhes bibliográficos
Main Authors: Pétursson, Gudmundur, Turelli, Priscilla, Matthíasdóttir, Sigrídur, Georgsson, Gudmundur, Andrésson, Ólafur S., Torsteinsdóttir, Sigurbjörg, Vigne, Robert, Andrésdóttir, Valgerdur, Gunnarsson, Eggert, Agnarsdóttir, Gudrún, Quérat, Gilles
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Viral Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC124651/
https://ncbi.nlm.nih.gov/pubmed/9445073
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