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Visna Virus dUTPase Is Dispensable for Neuropathogenicity

The major part of the dUTPase-encoding region of the visna virus genome was deleted. Intracerebral injection of the mutant virus resulted in a somewhat reduced viral load compared to that resulting from injection of the wild type, especially in the lungs, but the neuropathogenic effects were compara...

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Publicado no:J Virol
Principais autores: Pétursson, Gudmundur, Turelli, Priscilla, Matthíasdóttir, Sigrídur, Georgsson, Gudmundur, Andrésson, Ólafur S., Torsteinsdóttir, Sigurbjörg, Vigne, Robert, Andrésdóttir, Valgerdur, Gunnarsson, Eggert, Agnarsdóttir, Gudrún, Quérat, Gilles
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1998
Assuntos:
Viral Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC124651/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9445073/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.2.1657-1661.1998
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