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Oncolytic Vesicular Stomatitis Virus Induces Apoptosis via Signaling through PKR, Fas, and Daxx

Matrix (M) protein mutants of vesicular stomatitis virus (VSV) are promising oncolytic agents for cancer therapy. Previous research has implicated Fas and PKR in apoptosis induced by other viruses. Here, we show that dominant-negative mutants of Fas and PKR inhibit M protein mutant virus-induced apo...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Gaddy, Daniel F., Lyles, Douglas S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865982/
https://ncbi.nlm.nih.gov/pubmed/17192316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01760-06
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