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Oncolytic Vesicular Stomatitis Virus Induces Apoptosis via Signaling through PKR, Fas, and Daxx
Matrix (M) protein mutants of vesicular stomatitis virus (VSV) are promising oncolytic agents for cancer therapy. Previous research has implicated Fas and PKR in apoptosis induced by other viruses. Here, we show that dominant-negative mutants of Fas and PKR inhibit M protein mutant virus-induced apo...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2007
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1865982/ https://ncbi.nlm.nih.gov/pubmed/17192316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01760-06 |
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