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Gamma Interferon Responses of CD4 and CD8 T-Cell Subsets Are Quantitatively Different and Independent of Each Other during Pulmonary Mycobacterium bovis BCG Infection

Gamma interferon (IFN-γ) is a key cytokine in host defense against intracellular mycobacterial infection. It has been believed that both CD4 and CD8 T cells are the primary sources of IFN-γ. However, the relative contributions of CD4 and CD8 T-cell subsets to IFN-γ production and the relationship be...

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Autori principali: Ngai, Patricia, McCormick, Sarah, Small, Cherrie, Zhang, Xizhong, Zganiacz, Anna, Aoki, Naoko, Xing, Zhou
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865770/
https://ncbi.nlm.nih.gov/pubmed/17307945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00024-07
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