Intranasal Boosting with an Adenovirus-Vectored Vaccine Markedly Enhances Protection by Parenteral Mycobacterium bovis BCG Immunization against Pulmonary Tuberculosis

Parenterally administered Mycobacterium bovis BCG vaccine confers only limited immune protection from pulmonary tuberculosis in humans. There is a need for developing effective boosting vaccination strategies. We examined a heterologous prime-boost regimen utilizing BCG as a prime vaccine and our re...

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Detalhes bibliográficos
Main Authors: Santosuosso, Michael, McCormick, Sarah, Zhang, Xizhong, Zganiacz, Anna, Xing, Zhou
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1539608/
https://ncbi.nlm.nih.gov/pubmed/16861651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00517-06
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