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Mycobacterium bovis BCG Producing Interleukin-18 Increases Antigen-Specific Gamma Interferon Production in Mice

Interleukin-18 (IL-18) and IL-12 play a critical role in the expression of cell-mediated immunity involved in host defense against intracellular pathogens. Both cytokines are produced by macrophages and act in synergy to induce gamma interferon (IFN-γ) production by T, B, and natural killer cells. I...

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Detalhes bibliográficos
Main Authors: Biet, Franck, Kremer, Laurent, Wolowczuk, Isabelle, Delacre, Myriam, Locht, Camille
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC132979/
https://ncbi.nlm.nih.gov/pubmed/12438324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.12.6549-6557.2002
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