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Gas1 extends the range of Hedgehog action by facilitating its signaling
Cellular signaling initiated by Hedgehog binding to Patched1 has profound importance in mammalian embryogenesis, genetic disease, and cancer. Hedgehog acts as a morphogen to specify distinctive cell fates using different concentration thresholds, but our knowledge of how the concentration gradient i...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2007
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1865494/ https://ncbi.nlm.nih.gov/pubmed/17504940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1546307 |
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