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Gas1 extends the range of Hedgehog action by facilitating its signaling

Cellular signaling initiated by Hedgehog binding to Patched1 has profound importance in mammalian embryogenesis, genetic disease, and cancer. Hedgehog acts as a morphogen to specify distinctive cell fates using different concentration thresholds, but our knowledge of how the concentration gradient i...

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Bibliografski detalji
Glavni autori: Martinelli, David C., Fan, Chen-Ming
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865494/
https://ncbi.nlm.nih.gov/pubmed/17504940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1546307
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