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The Prp18 protein stabilizes the interaction of both exons with the U5 snRNA during the second step of pre-mRNA splicing
Interaction of the ends of the exons with loop 1 of the U5 snRNA aligns the exons for ligation in the second step of pre-mRNA splicing. To study the effect of Prp18 on the exons’ interactions, we analyzed the splicing of pre-mRNAs with random sequences in the exon bases at the splice junctions. The...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Cold Spring Harbor Laboratory Press
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1865492/ https://ncbi.nlm.nih.gov/pubmed/17504938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1538207 |
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