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The Prp18 protein stabilizes the interaction of both exons with the U5 snRNA during the second step of pre-mRNA splicing

Interaction of the ends of the exons with loop 1 of the U5 snRNA aligns the exons for ligation in the second step of pre-mRNA splicing. To study the effect of Prp18 on the exons’ interactions, we analyzed the splicing of pre-mRNAs with random sequences in the exon bases at the splice junctions. The...

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Bibliografiska uppgifter
Huvudupphovsmän: Crotti, Luciana B., Bačíková, Dagmar, Horowitz, David S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory Press 2007
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865492/
https://ncbi.nlm.nih.gov/pubmed/17504938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1538207
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