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Germline transcription from T-cell receptor Vβ gene is uncoupled from allelic exclusion

Allelic exclusion operates in B and T lymphocytes to ensure clonal expression of antigen receptors after V(D)J recombination. Germline transcription, which proceeds V(D)J recombination, has been postulated to provide an instructive signal for allelic exclusion. Here, we use a genetic marker to track...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Jia, Jingquan, Kondo, Motonari, Zhuang, Yuan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1864970/
https://ncbi.nlm.nih.gov/pubmed/17410206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601671
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