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Germline transcription from T-cell receptor Vβ gene is uncoupled from allelic exclusion
Allelic exclusion operates in B and T lymphocytes to ensure clonal expression of antigen receptors after V(D)J recombination. Germline transcription, which proceeds V(D)J recombination, has been postulated to provide an instructive signal for allelic exclusion. Here, we use a genetic marker to track...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1864970/ https://ncbi.nlm.nih.gov/pubmed/17410206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601671 |
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