Calcitonin and Prednisolone Display Antagonistic Actions on Bone and Have Synergistic Effects in Experimental Arthritis

We tested here the hypothesis that calcitonin and glucocorticoids, known to modulate bone metabolism, could have opposite actions on bone cells regulating expression of cytokine receptor activator of nuclear factor-κΒ ligand (RANKL) and osteoprotegerin (OPG). In the U2OS osteosarcoma cell line, calc...

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Detalhes bibliográficos
Main Authors: Mancini, Lucia, Paul-Clark, Mark J., Rosignoli, Guglielmo, Hannon, Robert, Martin, Jo E., Macintyre, Ian, Perretti, Mauro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2007
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1864877/
https://ncbi.nlm.nih.gov/pubmed/17322385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060830
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