Calcitonin and Prednisolone Display Antagonistic Actions on Bone and Have Synergistic Effects in Experimental Arthritis

We tested here the hypothesis that calcitonin and glucocorticoids, known to modulate bone metabolism, could have opposite actions on bone cells regulating expression of cytokine receptor activator of nuclear factor-κΒ ligand (RANKL) and osteoprotegerin (OPG). In the U2OS osteosarcoma cell line, calc...

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Dettagli Bibliografici
Autori principali: Mancini, Lucia, Paul-Clark, Mark J., Rosignoli, Guglielmo, Hannon, Robert, Martin, Jo E., Macintyre, Ian, Perretti, Mauro
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2007
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Regular Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1864877/
https://ncbi.nlm.nih.gov/pubmed/17322385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060830
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