Potent antiarthritic properties of a glucocorticoid derivative, NCX-1015, in an experimental model of arthritis

Here, we describe the improved antiarthritic properties of a nitric oxide-releasing derivative of prednisolone that includes a sparing of the effects on bone. Glucocorticoids are widely used in the treatment of chronic inflammatory pathologies, but their use is often accompanied by side effects, inc...

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Bibliographic Details
Main Authors: Paul-Clark, Mark J., Mancini, Lucia, Del Soldato, Piero, Flower, Roderick J., Perretti, Mauro
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2002
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC122250/
https://ncbi.nlm.nih.gov/pubmed/11805287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.022641099
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