The lytic switch protein of KSHV activates gene expression via functional interaction with RBP-Jκ (CSL), the target of the Notch signaling pathway

The RTA protein of the Kaposi's sarcoma (KS)-associated herpesvirus (KSHV) is responsible for the switch from latency to lytic replication, a reaction essential for viral spread and KS pathogenesis. RTA is a sequence-specific transcriptional activator, but the diversity of its target sites sugg...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Liang, Yuying, Chang, Jean, Lynch, Stephen J., Lukac, David M., Ganem, Don
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory Press 2002
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC186409/
https://ncbi.nlm.nih.gov/pubmed/12154127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.996502
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk