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Cyclin D–cdk4 activity modulates the subnuclear localization and interaction of MEF2 with SRC-family coactivators during skeletal muscle differentiation

Prior work has indicated that D-type cyclin–cdk4 complexes, which are only active in proliferating cells, can suppress the skeletal muscle differentiation program in proliferating myoblasts. In this study, we show that cyclin D–cdk activity can block the activity of the MEF2 family of transcriptiona...

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Bibliographic Details
Published in:Genes Dev
Main Authors: Lazaro, Jean-Bernard, Bailey, Peter J., Lassar, Andrew B.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2002
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC186397/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12130539/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.U-9988R
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