Ligand-independent recruitment of steroid receptor coactivators to estrogen receptor by cyclin D1

The estrogen receptor (ER) is an important regulator of growth and differentiation of breast epithelium. Transactivation by ER depends on a leucine-rich motif, which constitutes a ligand-regulated binding site for steroid receptor coactivators (SRCs). Cyclin D1 is frequently amplified in breast canc...

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Main Authors: Zwijsen, Renate M.L., Buckle, Robin S., Hijmans, E. Marielle, Loomans, Cindy J.M., Bernards, René
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 1998
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC317237/
https://ncbi.nlm.nih.gov/pubmed/9832502
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