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Ligand-independent recruitment of steroid receptor coactivators to estrogen receptor by cyclin D1

The estrogen receptor (ER) is an important regulator of growth and differentiation of breast epithelium. Transactivation by ER depends on a leucine-rich motif, which constitutes a ligand-regulated binding site for steroid receptor coactivators (SRCs). Cyclin D1 is frequently amplified in breast canc...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Genes Dev
Hauptverfasser: Zwijsen, Renate M.L., Buckle, Robin S., Hijmans, E. Marielle, Loomans, Cindy J.M., Bernards, René
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 1998
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317237/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9832502/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.22.3488
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