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Structural and biochemical characterization of human orphan DHRS10 reveals a novel cytosolic enzyme with steroid dehydrogenase activity

To this day, a significant proportion of the human genome remains devoid of functional characterization. In this study, we present evidence that the previously functionally uncharacterized product of the human DHRS10 gene is endowed with 17β-HSD (17β-hydroxysteroid dehydrogenase) activity. 17β-HSD e...

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Détails bibliographiques
Auteurs principaux: Lukacik, Petra, Keller, Brigitte, Bunkoczi, Gabor, Kavanagh, Kathryn, Hwa Lee, Wen, Adamski, Jerzy, Oppermann, Udo
Format: Artigo
Langue:Inglês
Publié: Portland Press Ltd. 2007
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1863559/
https://ncbi.nlm.nih.gov/pubmed/17067289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061319
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