Rap1–Sir4 binding independent of other Sir, yKu, or histone interactions initiates the assembly of telomeric heterochromatin in yeast

In Saccharomyces cerevisiae, heterochromatin-like regions are found near telomeres and at the silent mating-type loci, where they can repress genes in an epigenetic manner. Several proteins are involved in telomeric heterochromatin structure including Rap1, Sir2, Sir3, Sir4, yKu70 (Hdf1), yKu80 (Hdf...

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發表在:	Genes Dev
Principais autores:	Luo, Kunheng, Vega-Palas, Miguel A., Grunstein, Michael
格式:	Artigo
語言:	Inglês
出版:	Cold Spring Harbor Laboratory Press 2002
主題:	Research Paper
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC186350/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12080091/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.988802
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