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Rap1–Sir4 binding independent of other Sir, yKu, or histone interactions initiates the assembly of telomeric heterochromatin in yeast

In Saccharomyces cerevisiae, heterochromatin-like regions are found near telomeres and at the silent mating-type loci, where they can repress genes in an epigenetic manner. Several proteins are involved in telomeric heterochromatin structure including Rap1, Sir2, Sir3, Sir4, yKu70 (Hdf1), yKu80 (Hdf...

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Bibliografiske detaljer
Main Authors: Luo, Kunheng, Vega-Palas, Miguel A., Grunstein, Michael
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC186350/
https://ncbi.nlm.nih.gov/pubmed/12080091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.988802
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