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Negative regulation of the RIG-I signaling by the ubiquitin ligase RNF125
Retinoic acid-inducible gene I (RIG-I) plays a pivotal role in the regulation of cytokine production induced by pathogens. The RIG-I also augments the production of IFN and other cytokines via an amplification circuit. Because the production of cytokines is closely controlled, up- and down-regulatio...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1863485/ https://ncbi.nlm.nih.gov/pubmed/17460044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611551104 |
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