Monocyte-derived dendritic cells loaded with a mixture of apoptotic/necrotic melanoma cells efficiently cross-present gp100 and MART-1 antigens to specific CD8(+ )T lymphocytes

BACKGROUND: In the present study, we demonstrate, in rigorous fashion, that human monocyte-derived immature dendritic cells (DCs) can efficiently cross-present tumor-associated antigens when co-cultured with a mixture of human melanoma cells rendered apoptotic/necrotic by γ irradiation (Apo-Nec cell...

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Main Authors: von Euw, Erika M, Barrio, María M, Furman, David, Bianchini, Michele, Levy, Estrella M, Yee, Cassian, Li, Yongqing, Wainstok, Rosa, Mordoh, José
格式: Artigo
語言:Inglês
出版: BioMed Central 2007
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1863425/
https://ncbi.nlm.nih.gov/pubmed/17448240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-5-19
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