MLANA/MART1 and SILV/PMEL17/GP100 Are Transcriptionally Regulated by MITF in Melanocytes and Melanoma

The clinically important melanoma diagnostic antibodies HMB-45, melan-A, and MITF (D5) recognize gene products of the melanocyte-lineage genes SILV/PMEL17/GP100, MLANA/MART1, and MITF, respectively. MITF encodes a transcription factor that is essential for normal melanocyte development and appears t...

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Detalhes bibliográficos
Main Authors: Du, Jinyan, Miller, Arlo J., Widlund, Hans R., Horstmann, Martin A., Ramaswamy, Sridhar, Fisher, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2003
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868174/
https://ncbi.nlm.nih.gov/pubmed/12819038
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