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The secreted form of a melanocyte membrane-bound glycoprotein (Pmel17/gp100) is released by ectodomain shedding

Ectodomain shedding is a proteolytic mechanism by which a transmembrane protein is converted into a secreted form. Pmel17/gp100 is a melanocyte-specific membrane-bound glycoprotein that has amyloid characteristics and forms fibrillar structures in melanosomes after a complex sequence of post-transla...

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Detalhes bibliográficos
Main Authors: Hoashi, Toshihiko, Tamaki, Kunihiko, Hearing, Vincent J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Federation of American Societies for Experimental Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830135/
https://ncbi.nlm.nih.gov/pubmed/19884326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-140921
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