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Pneumolysin stimulates production of tumor necrosis factor alpha and interleukin-1 beta by human mononuclear phagocytes.

Human peripheral blood monocytes and a human monocyte cell line were exposed to the toxin pneumolysin. Pneumolysin-exposed cells produced significantly larger amounts of tumor necrosis factor alpha and interleukin-1 beta than cells not exposed to the toxin. The viability of cells was not affected by...

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Библиографические подробности
Главные авторы: Houldsworth, S, Andrew, P W, Mitchell, T J
Формат: Artigo
Язык:Inglês
Опубликовано: 1994
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC186313/
https://ncbi.nlm.nih.gov/pubmed/8132361
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