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Pneumolysin stimulates production of tumor necrosis factor alpha and interleukin-1 beta by human mononuclear phagocytes.

Human peripheral blood monocytes and a human monocyte cell line were exposed to the toxin pneumolysin. Pneumolysin-exposed cells produced significantly larger amounts of tumor necrosis factor alpha and interleukin-1 beta than cells not exposed to the toxin. The viability of cells was not affected by...

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Detalhes bibliográficos
Publicado no:Infect Immun
Principais autores: Houldsworth, S, Andrew, P W, Mitchell, T J
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC186313/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8132361/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.62.4.1501-1503.1994
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