Pneumolysin stimulates production of tumor necrosis factor alpha and interleukin-1 beta by human mononuclear phagocytes.

Human peripheral blood monocytes and a human monocyte cell line were exposed to the toxin pneumolysin. Pneumolysin-exposed cells produced significantly larger amounts of tumor necrosis factor alpha and interleukin-1 beta than cells not exposed to the toxin. The viability of cells was not affected by...

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Veröffentlicht in:	Infect Immun
Hauptverfasser:	Houldsworth, S, Andrew, P W, Mitchell, T J
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1994
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC186313/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8132361/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.62.4.1501-1503.1994
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