Amyloid beta protein deposition in normal aging has the same characteristics as that in Alzheimer's disease. Predominance of A beta 42(43) and association of A beta 40 with cored plaques.

Two distinct species of amyloid beta protein (A beta) with different C-termini, A beta 42(43) and A beta 40, are deposited in senile plaques (SP) of Alzheimer's disease (AD), with the former being far predominant. To investigate whether A beta 42(43) also predominates over A beta 40 in normal a...

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Bibliographic Details
Main Authors: Fukumoto, H., Asami-Odaka, A., Suzuki, N., Shimada, H., Ihara, Y., Iwatsubo, T.
Format: Artigo
Language:Inglês
Published: 1996
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1861616/
https://ncbi.nlm.nih.gov/pubmed/8546214
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