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A brain-enriched polypyrimidine tract-binding protein antagonizes the ability of Nova to regulate neuron-specific alternative splicing

The Nova paraneoplastic antigens are neuron-specific RNA binding proteins that participate in the control of alternative splicing. We have used the yeast two-hybrid system to isolate Nova interacting proteins and identify an RNA binding protein that is closely related to the polypyrimidine tract-bin...

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Библиографические подробности
Главные авторы: Polydorides, Alexandros D., Okano, Hirotaka J., Yang, Yolanda Y. L., Stefani, Giovanni, Darnell, Robert B.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2000
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC18606/
https://ncbi.nlm.nih.gov/pubmed/10829067
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