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A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons

Many metazoan gene transcripts exhibit neuron-specific splicing patterns, but the developmental control of these splicing events is poorly understood. We show that the splicing of a large group of exons is reprogrammed during neuronal development by a switch in expression between two highly similar...

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מידע ביבליוגרפי
Main Authors: Boutz, Paul L., Stoilov, Peter, Li, Qin, Lin, Chia-Ho, Chawla, Geetanjali, Ostrow, Kristin, Shiue, Lily, Ares, Manuel, Black, Douglas L.
פורמט: Artigo
שפה:Inglês
יצא לאור: Cold Spring Harbor Laboratory Press 2007
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899473/
https://ncbi.nlm.nih.gov/pubmed/17606642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1558107
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