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Enantiomer discrimination illustrated by high-resolution crystal structures of the human nuclear receptor hRARγ
The human retinoic acid receptor (hRAR) is a member of the nuclear receptor superfamily that regulates the transcription of target genes in a ligand-dependent manner. The three hRAR isotypes are targets for retinoids that are used in the treatment of various diseases, including breast cancer and ski...
Shranjeno v:
| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2000
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC18601/ https://ncbi.nlm.nih.gov/pubmed/10841540 |
| Oznake: |
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