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Novel dexamethasone-HPMA copolymer conjugate and its potential application in treatment of rheumatoid arthritis

Rheumatoid arthritis (RA) is a chronic autoimmune disease of unknown etiology. Effective treatment of this disorder has been hampered by the lack of availability of agents that selectively target affected joint tissue. We developed a novel pH-sensitive drug delivery system of dexamethasone (Dex) bas...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wang, Dong, Miller, Scott C, Liu, Xin-Ming, Anderson, Brian, Wang, Xu Sherry, Goldring, Steven R
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1860059/
https://ncbi.nlm.nih.gov/pubmed/17233911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2106
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