Activation of hepatic stellate cells by TGF alpha and collagen type I is mediated by oxidative stress through c-myb expression.
Excessive production of collagen type I is a major contributor to hepatic fibrosis. Activated (myofibroblastic), but not quiescent, hepatic stellate cells (lipocytes) have a high level of collagen type I and alpha-smooth muscle actin expression. Therefore, stellate cell activation is a critical step...
Na minha lista:
| 發表在: | J Clin Invest |
|---|---|
| Principais autores: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Clinical Investigation
1995
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185899/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7593635/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118304 |
| 標簽: |
沒有標簽, 成為第一個標記此記錄!
|