Identification of a new susceptibility locus for insulin-dependent diabetes mellitus by ancestral haplotype congenic mapping.

The number and exact locations of the major histocompatibility complex (MHC)-linked diabetogenic genes (Idd-1) are unknown because of strong linkage disequilibrium within the MHC. By using a congenic NOD mouse strain that possesses a recombinant MHC from a diabetes-resistant sister strain, we have n...

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Publicado en:	J Clin Invest
Autores principales:	Ikegami, H, Makino, S, Yamato, E, Kawaguchi, Y, Ueda, H, Sakamoto, T, Takekawa, K, Ogihara, T
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Clinical Investigation 1995
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185830/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7560085/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118239
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