Identification of a new susceptibility locus for insulin-dependent diabetes mellitus by ancestral haplotype congenic mapping.

The number and exact locations of the major histocompatibility complex (MHC)-linked diabetogenic genes (Idd-1) are unknown because of strong linkage disequilibrium within the MHC. By using a congenic NOD mouse strain that possesses a recombinant MHC from a diabetes-resistant sister strain, we have n...

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Autors principals: Ikegami, H, Makino, S, Yamato, E, Kawaguchi, Y, Ueda, H, Sakamoto, T, Takekawa, K, Ogihara, T
Format: Artigo
Idioma:Inglês
Publicat: 1995
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC185830/
https://ncbi.nlm.nih.gov/pubmed/7560085
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