Angiotensin converting enzyme expression is increased in small pulmonary arteries of rats with hypoxia-induced pulmonary hypertension.

Previous studies suggest that while lung angiotensin converting enzyme (ACE) activity is reduced during chronic hypoxia, inhibitors of ACE attenuate hypoxic pulmonary hypertension. In an attempt to explain this paradox we investigated the possibility that whole lung ACE activity may not reflect loca...

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Pubblicato in:	J Clin Invest
Autori principali:	Morrell, N W, Atochina, E N, Morris, K G, Danilov, S M, Stenmark, K R
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185819/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7560074/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118228
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