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Angiotensin converting enzyme expression is increased in small pulmonary arteries of rats with hypoxia-induced pulmonary hypertension.

Previous studies suggest that while lung angiotensin converting enzyme (ACE) activity is reduced during chronic hypoxia, inhibitors of ACE attenuate hypoxic pulmonary hypertension. In an attempt to explain this paradox we investigated the possibility that whole lung ACE activity may not reflect loca...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Morrell, N W, Atochina, E N, Morris, K G, Danilov, S M, Stenmark, K R
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185819/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7560074/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118228
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