Angiotensin converting enzyme expression is increased in small pulmonary arteries of rats with hypoxia-induced pulmonary hypertension.

Previous studies suggest that while lung angiotensin converting enzyme (ACE) activity is reduced during chronic hypoxia, inhibitors of ACE attenuate hypoxic pulmonary hypertension. In an attempt to explain this paradox we investigated the possibility that whole lung ACE activity may not reflect loca...

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Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	Morrell, N W, Atochina, E N, Morris, K G, Danilov, S M, Stenmark, K R
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 1995
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185819/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7560074/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118228
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