Evidence that epithelial glycoprotein 330/megalin mediates uptake of polybasic drugs.

Glycoprotein 330 (gp330) is an endocytic receptor expressed in the renal proximal tubules and some other absorptive epithelia, e.g., in the inner ear. The present study shows that the antifibrinolytic polypeptide, aprotinin, and the nephro- and ototoxic antibiotics, aminoglycosides, and polymyxin B...

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Bibliografski detalji
Glavni autori: Moestrup, S K, Cui, S, Vorum, H, Bregengård, C, Bjørn, S E, Norris, K, Gliemann, J, Christensen, E I
Format: Artigo
Jezik:Inglês
Izdano: 1995
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC185763/
https://ncbi.nlm.nih.gov/pubmed/7544804
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